One-pot synthesis, characterisation and biological activities of gold nanoparticles prepared using aqueous seed extract of Garcinia kola

Recently, biogenic synthesis of gold nanoparticles (AuNPs) has become a focus area in cancer research owing to the eco-friendliness and cost effectiveness synthetic method. In this study, aqueous extract Garcinia kola seed (AEGKs) was used for bio-reduction Au3+ Au0. The synthesised AEGKs-AuNPs characterised by ultraviolet-visible (UV-Vis) spectroscopy, dynamic light scattering (DLS), high-resolution transmission electron microscopy (HRTEM) Fourier transform-infrared (FT-IR) spectroscopy. vitro antioxidant activity AEGKs evaluated using 2,2-diphenyl-1-picrylhydrazyl radical scavenging ability ferric reducing power assays. showed an absorption maximum at 512 nm, HRTEM images revealed mostly, spherical-shaped AuNPs size range 2–17 nm. FT-IR spectroscopy that polyphenolic compounds proteins were predominant, responsible reduction capping AuNPs. concentration dependent activities, while dose-dependent anti-cancer demonstrated against lungs, prostrate, human cervical colon cells, 3-(4,5-dimethylthiazol-2-yl)− 2,5-diphenyltetrazolium bromide tetrazolium (MTT) assay. activities could be attributed presence phytochemicals physicochemical properties